Matt Busch was born in Lebanon, Pennsylvania on September 22, 1972, to Frederick and Peggy Busch. He grew up in the northern suburbs of Detroit, Michigan and became obsessed with creating his own Star Wars pop-up books and self-published comic books. After earning an associate degree from Macomb Community College, he moved to Pasadena, California, where he attended the Los Angeles Art Academy, and received a bachelor's degree from the Art Center College of Design.

Since 1994, Matt Busch has provided art for official Star Wars books, posters, magazines, and other products. Early in his career, Busch started illustrating products for the Star Wars: The Roleplaying Game and the cover for Star Wars: Tales from the Empire, which became a New York Times Best Seller. One of his more recent projects was illustrating the Style D One Sheet movie poster for Star Wars: Episode III – Revenge of the Sith.

Busch is perhaps best known for his outspoken antics in the You Can Draw Star Wars video series, which is based on the book of the same name, which he also illustrated. The video series was first released online and later released on DVD. Following that, the videos found even more success when they were released on MySpace.com, and shot straight to number one on their charts. Volume Two of the same tutorial series was also released on DVD.

In 2008, Hasbro released a droid action figure named MB-RA-7, which was named after Matt Busch. Also that year, Busch became the first Honorary Member of the 501st Legion of Stormtroopers to become an official member with his own TK Stormtrooper armor.

In October 2009, he created and released Zombie Wars Episode I: The Zombie Menace, Zombie Wars Episode II: Attack of the Undead, Zombie Wars Episode III: Revenge of the Zombies, Zombie Wars Episode IV: A New Epidemic, Zombie Wars Episode V: The Living Dead Strike Back, and Zombie Wars Episode VI: Return from the Grave. A couple of months later, Kohl's department stores re-released an exclusive Boba Fett T-shirt featuring Busch's art.

Matt has illustrated CD covers and posters for rock bands, films and storyboarded some of your most iconic movies in the industry.

Busch married his wife Lin Zy (née Selestow), a puppet designer, on September 18, 2011, in Royal Palm Beach, Florida. They reside in a multiple-studio house in Macomb Township, Michigan with their dog Roxie.